Flea Control

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This table was generated by locating the various available flea, tick and heartworm medications, and compiling data from the manufacturers product labeling (where available) or the website information. The two highlighted in green are ultimately what I decided to go with.


Product Manufacturer Type Fleas Ticks Mosquitoes Heartworms Parasites Cat-Safe[1] Risk[2] Prescription Ingredient
Advantage II Bayer Topical Egg, Larvae, Adult Icon Red X.png Icon Red X.png Icon Red X.png Lice Icon Green Check.png Icon Red X.png Icon Red X.png Imidacloprid + Pyriproxyfen IGR
Advantage Multi Bayer Topical Adult[3] Icon Red X.png Icon Red X.png Icon Green Check.png Round, Hook, Round And Whipworms Icon Red X.png MDR1 Icon Red X.png Imidacloprid + Moxidectin
Advantix II Bayer Topical Egg, Larvae, Adult Icon Green Check.png Icon Green Check.png Icon Red X.png Lice Icon Red X.png Icon Red X.png Icon Red X.png Imidacloprid + Permethrin + Pyriproxyfen IGR
bioSpot Farnam Topical Egg, Adult Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Permethrin + (S)-Methoprine
Capstar Novartis Oral Adult Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Red X.png Nitenpyram
Certifect Merial Topical Egg, Larvae, Adult Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Red X.png Fipronil + (S)-Methoprene + Amitrax
Comfortis Elanco/Lilly Oral Adult Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Green Check.png Spinosad
Ecto Advance Meridian Topical Egg, Larvae, Adult Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Red X.png Fipronil + (S)-methoprene
Frontline Top Spot Merial Topical Adult Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Red X.png Fipronil
Frontline Plus Merial Topical Egg, Larvae, Adult Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Red X.png Fipronil + (S)-methoprene
Heartgard Merial Oral Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Ascarids, Hookworm Icon Green Check.png Icon Red X.png Icon Green Check.png Ivermectin + Pyrantel
Interceptor Novartis Oral Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Round, Hook, And Whipworm Icon Green Check.png Icon Red X.png Icon Green Check.png Milbemycin Oxime
Iverhart-Max Virbac Oral Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Round, Hook, Whip And Tapeworm Icon Green Check.png MDR1 Icon Green Check.png Ivermectin + Pyrantel Pamoate + Praziquantel
Program Novartis Oral Egg Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Icon Red X.png Icon Red X.png Lufenuron
Promeris Ford Dodge Topical Adult Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Metaflumizone + Amitraz
Revolution Pfizer Topical Egg, Adult Icon Green Check.png Icon Red X.png Icon Green Check.png Ear & Sarcoptic Mites, American Dog Tick Icon Green Check.png Icon Red X.png Icon Green Check.png Selemectin
Sentinel Novartis Oral Egg, Larvae Icon Red X.png Icon Red X.png Icon Green Check.png Hook, Round And Whipworm Icon Green Check.png Icon Red X.png Icon Green Check.png Milbemycin Oxime + Lufenuron
Trifexis Elanco/Lilly Oral Adult Icon Red X.png Icon Red X.png Icon Green Check.png Hook, Round And Whipworm Icon Green Check.png Icon Red X.png Icon Green Check.png Milbemycin Oxime + Spinosad
Tri-Force Agri-Labs Topical Egg, Larvae, Adult Icon Green Check.png Icon Green Check.png Icon Green Check.png Icon Red X.png Icon Red X.png Icon Red X.png Icon Red X.png Cyphenothrin
Tri-Heart Plus Intervet Oral Icon Red X.png Icon Red X.png Icon Red X.png Icon Green Check.png Ascarids, Hookworms Icon Green Check.png MDR1 Icon Green Check.png Ivermectin + Pyrantel

Notes

  1. "Cat Safe" means the risk to cats in the presence of dogs dosed with a given medication. The non-cat safe ones generally recommended NOT using them if the household has cats, or the dog is in an area where a cat may come in contact with the drug. In a later revision I plan to link to more detailed information on the drug, if available.
  2. "Risk" indicates a known risk. Most of these drugs indicate some small degree of issues in certain animals (sick, weak, under-age, etc). Many herding dog breeds are afflicted with a mutation of the multi-drug resistance (MDR1) gene. This gene encodes a protein (P-glycoprotein) that is responsible for removing certain drugs and toxins from the brain. Dogs that carry the mdr1 genetic defect cannot rid their brains of the problem drugs. The result is a neurotoxic buildup that can cause abnormal neurological symptoms and/or death.
  3. Kills adult fleas on dogs, larvae on contact with treated dog